Betanidine
- Product Name
- Betanidine
- CAS No.
- 55-73-2
- Chemical Name
- Betanidine
- Synonyms
- BETANIDIN;Betanidine;Bethanidine;Betanidine USP/EP/BP;1-Benzyl-2,3-dimethylguanidine;2-benzyl-1,3-diMethylguanidine;N,N'-Dimethyl-N''-(phenylmethyl)guanidine;Guanidine, N,N''-dimethyl-N'-(phenylmethyl)-
- CBNumber
- CB11116819
- Molecular Formula
- C10H15N3
- Formula Weight
- 177.25
- MOL File
- 55-73-2.mol
Betanidine Property
- Melting point:
- 195-197°
- Boiling point:
- 299.18°C (rough estimate)
- Density
- 0.9826 (rough estimate)
- refractive index
- 1.4800 (estimate)
- pka
- pKa 10.6 (Uncertain)
N-Bromosuccinimide Price
- Product number
- API0008204
- Product name
- BETHANIDINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.23
- Updated
- 2021/12/16
Betanidine Chemical Properties,Usage,Production
Originator
Bendogen,Lagap Pharmaceuticals SA
Uses
Betanidine is a betacyanin and an aglycone of the beet dye betanin.
Definition
ChEBI: Bethanidine is a member of guanidines. It has a role as an adrenergic antagonist and an antihypertensive agent.
Manufacturing Process
A mixture of 2-bromobenzylamine (12.5 g) and S-methylthiouronium sulfate (10 g) in water (20 ml) was heated for 1.5 hours on a steam bath in a hood, during which methylmercaptan escaped (as evidenced by a foul odour). The reaction mixture was then cooled and diluted with ethanol (100 ml). A colourless solid of 2-bromobenzylguanidine sulfate was separeted, and washed with ethanol. This solid melted at 230-232°C; it was recrystallized from water and then melted at 247-248°C. By action of a basic agent the salt obtained may be converted into free base.
Therapeutic Function
Antihypertensive